Article
Variations in CCR5, but not HFE, ELMO1, or SLC12A3, are associated with susceptibility to kidney disease in north Indian individuals with type 2 diabetes.
Journal of diabetes - 1 Nov 2014
Yadav Ashok K, Kumar Vinod, Dutta Pinaki, Bhansali Anil, Jha Vivekanand
Abstract excerpt
BACKGROUND: Diabetic nephropathy (DN), the leading cause of end-stage renal disease worldwide, may have a genetic component. In the present study, we investigated variations in a set of genes with susceptibility to DN in a north Indian population. METHODS: Four genes (HFE, ELMO1, SLC12A3, and CCR5) were selected on the basis of reported association with type 2 diabetes and nephropathy. In all, 417 diabetic...
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