Article
Serpin Family E Member 1 Tag Single-Nucleotide Polymorphisms in Patients with Diabetic Nephropathy: An Association Study and Meta-Analysis Using a Genetic Model-Free Approach.
Genes - 25 Nov 2021
Tziastoudi Maria, Dardiotis Efthimios, Pissas Georgios, Filippidis Georgios, Golfinopoulos Spyridon, Siokas Vasileios, Tachmitzi Sophia V, Eleftheriadis Theodoros, Hadjigeorgiou Georgios M, Tsironi Evangelia, Stefanidis Ioannis
Abstract excerpt
BACKGROUND: Many lines of evidence highlight the genetic contribution on the development of diabetic nephropathy (DN). One of the studied genes is SERPINE1 whose the role in the risk of developing DN remains questionable. In order to elucidate the contribution of SERPINE1 in DN progression in the context of type 2 diabetes mellitus (T2DM), we conducted an association study and meta-analysis of SERPINE1 genetic...
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