Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monitoring of Pseudomonas aeruginosa mutational resistome dynamics using an enrichment panel for direct sequencing of clinical samples.

EBioMedicine - 1 Oct 2024

Cortes-Lara Sara, Medina-Reatiga Paola, Barrio-Tofiño Ester Del, Gomis-Font María A, Cabot Gabriel, Gómez-Romano Fernando, Ayestarán Ignacio, Colomar Asunción, Palou-Rotger Alexandre, Oteo-Iglesias Jesús, Campo Rosa Del, Cantón Rafael, Horcajada Juan P, López-Causapé Carla, Oliver Antonio

Abstract excerpt

BACKGROUND: Pseudomonas aeruginosa is a major cause of hospital-acquired and chronic infections, characterised by an extraordinary capacity to develop antimicrobial resistance through the selection of chromosomal mutations, leading to treatment failure. Here, we designed and tested a hybridisation-based capture system for the enrichment of genes of interest before sequencing to monitor resistant populations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Microbial Sensitivity Tests

Share to Multilocus Sequence Typing

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 39332391
DOI: 10.1016/j.ebiom.2024.105367
PMCID: PMC11467565

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monitoring of Pseudomonas aeruginosa mutational resistome dynamics using an enrichment panel for direct sequencing of clinical samples.PMID 39332391Read ↗

Deciphering the Resistome of the Widespread Pseudomonas aeruginosa Sequence Type 175 International High-Risk Clone through Whole-Genome Sequencing.Semantic proximity Read ↗

Keeping up with the pathogens: improved antimicrobial resistance detection and prediction from Pseudomonas aeruginosa genomes.Semantic proximity Read ↗

Keeping up with the pathogens: Improved antimicrobial resistance detection and prediction from<i>Pseudomonas</i>aeruginosa genomesSemantic proximity Read ↗

Correlation between phenotypic antibiotic susceptibility and the resistome in Pseudomonas aeruginosa.Semantic proximity Read ↗

Genome Capture Sequencing Selectively Enriches Bacterial DNA and Enables Genome-Wide Measurement of Intrastrain Genetic Diversity in Human Infections.Semantic proximity Read ↗

Hypermutator <i>Pseudomonas aeruginosa</i> exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patientsSemantic proximity Read ↗

Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients.Semantic proximity Read ↗

PaREx: an open-source pipeline for the automated analysis of Pseudomonas aeruginosa resistomes from whole-genome sequences.Semantic proximity Read ↗

Within-patient evolution of Pseudomonas aeruginosa populations during antimicrobial treatment.Semantic proximity Read ↗

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone.Semantic proximity Read ↗

Within-Patient Evolution of <i>Pseudomonas aeruginosa</i> Populations During Antimicrobial TreatmentSemantic proximity Read ↗

Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.