Article
Correlation between phenotypic antibiotic susceptibility and the resistome in Pseudomonas aeruginosa.
International journal of antimicrobial agents - 1 Aug 2017
Jaillard Magali, van Belkum Alex, Cady Kyle C, Creely David, Shortridge Dee, Blanc Bernadette, Barbu E Magda, Dunne W Michael, Zambardi Gilles, Enright Mark, Mugnier Nathalie, Le Priol Christophe, Schicklin Stéphane, Guigon Ghislaine, Veyrieras Jean-Baptiste
Abstract excerpt
Genetic determinants of antibiotic resistance (AR) have been extensively investigated. High-throughput sequencing allows for the assessment of the relationship between genotype and phenotype. A panel of 672 Pseudomonas aeruginosa strains was analysed, including representatives of globally disseminated multidrug-resistant and extensively drug-resistant clones; genomes and multiple antibiograms were available. This...
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