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Hypermutator <i>Pseudomonas aeruginosa</i> exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patients

2019-10-17

Abstract excerpt

<h4>ABSTRACT</h4> Pseudomonas aeruginosa exploits intrinsic and acquired resistance mechanisms to resist almost every antibiotic used in chemotherapy. Antimicrobial resistance in P. aeruginosa isolated from cystic fibrosis (CF) patients is further enhanced by the occurrence of hypermutator strains, a hallmark of chronic CF infections. However, the within-patient genetic diversity of P. aeruginosa populations re...

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Literature Corpus work
56e5a677-96dd-5094-a147-710328fdab22
DOI
10.1101/809319
Open publication

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Hypermutator <i>Pseudomonas aeruginosa</i> exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patientsDOI 10.1101/809319
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