Article
Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone.
Scientific reports - 17 Jul 2017
López-Causapé Carla, Sommer Lea Mette, Cabot Gabriel, Rubio Rosa, Ocampo-Sosa Alain A, Johansen Helle Krogh, Figuerola Joan, Cantón Rafael, Kidd Timothy J, Molin Soeren, Oliver Antonio
Abstract excerpt
Emergence of epidemic clones and antibiotic resistance development compromises the management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections. Whole genome sequencing (WGS) was used to decipher the phylogeny, interpatient dissemination, WGS mutator genotypes (mutome) and resistome of a widespread clone (CC274), in isolates from two highly-distant countries, Australia and Spain,...
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