Article
Keeping up with the pathogens: improved antimicrobial resistance detection and prediction from Pseudomonas aeruginosa genomes.
Genome medicine - 7 Jun 2024
Madden Danielle E, Baird Timothy, Bell Scott C, McCarthy Kate L, Price Erin P, Sarovich Derek S
Abstract excerpt
BACKGROUND: Antimicrobial resistance (AMR) is an intensifying threat that requires urgent mitigation to avoid a post-antibiotic era. Pseudomonas aeruginosa represents one of the greatest AMR concerns due to increasing multi- and pan-drug resistance rates. Shotgun sequencing is gaining traction for in silico AMR profiling due to its unambiguity and transferability; however, accurate and comprehensive AMR...
Topics
- Pseudomonas aeruginosa
- Genome, Bacterial
- Drug Resistance, Bacterial
- Anti-Bacterial Agents
- Humans
- Genomics
- Pseudomonas Infections
- Microbial Sensitivity Tests
- Databases, Genetic
- Phenotype