Article
Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients.
Antimicrobial agents and chemotherapy - 21 Apr 2020
Colque C A, Albarracín Orio A G, Feliziani S, Marvig R L, Tobares A R, Johansen H K, Molin S, Smania A M
Abstract excerpt
Pseudomonas aeruginosa exploits intrinsic and acquired resistance mechanisms to resist almost every antibiotic used in chemotherapy. Antimicrobial resistance in P. aeruginosa isolates recovered from cystic fibrosis (CF) patients is further enhanced by the occurrence of hypermutator strains, a hallmark of chronic infections in CF patients. However, the within-patient genetic diversity of P. aeruginosa populations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.