Deciphering the Resistome of the Widespread Pseudomonas aeruginosa Sequence Type 175 International High-Risk Clone through Whole-Genome Sequencing.

doi:10.1128/AAC.01720-16

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Deciphering the Resistome of the Widespread Pseudomonas aeruginosa Sequence Type 175 International High-Risk Clone through Whole-Genome Sequencing.

Antimicrobial agents and chemotherapy - 1 Dec 2016

Cabot Gabriel, López-Causapé Carla, Ocampo-Sosa Alain A, Sommer Lea M, Domínguez María Ángeles, Zamorano Laura, Juan Carlos, Tubau Fe, Rodríguez Cristina, Moyà Bartolomé, Peña Carmen, Martínez-Martínez Luis, Plesiat Patrick, Oliver Antonio

Abstract excerpt

Whole-genome sequencing (WGS) was used for the characterization of the frequently extensively drug resistant (XDR) Pseudomonas aeruginosa sequence type 175 (ST175) high-risk clone. A total of 18 ST175 isolates recovered from 8 different Spanish hospitals were analyzed; 4 isolates from 4 different French hospitals were included for comparison. The typical resistance profile of ST175 included penicillins,...

Topics

Aminoglycosides
Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
Cephalosporins
Clone Cells
Drug Resistance, Multiple, Bacterial
Fluoroquinolones
France

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Genome, Bacterial

High-Throughput Nucleotide Sequencing

Hospitals

Humans

Microbial Sensitivity Tests

Monobactams

Mutation

Penicillins

Source

Open in PubMed Open full text

Identifiers

PMID: 27736752
DOI: 10.1128/AAC.01720-16
PMCID: PMC5119024

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