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Article

The HUNT lung-SNP model: genetic variants plus clinical variables improve lung cancer risk assessment over clinical models.

Journal of cancer research and clinical oncology - 12 Aug 2024

Nguyen Olav Toai Duc, Fotopoulos Ioannis, Nøst Therese Haugdahl, Markaki Maria, Lagani Vincenzo, Tsamardinos Ioannis, Røe Oluf Dimitri

Abstract excerpt

PURPOSE: The HUNT Lung Cancer Model (HUNT LCM) predicts individualized 6-year lung cancer (LC) risk among individuals who ever smoked cigarettes with high precision based on eight clinical variables. Can the performance be improved by adding genetic information? METHODS: A polygenic model was developed in the prospective Norwegian HUNT2 study with clinical and genotype data of individuals who ever smoked...

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Identifiers

PMID: 39129029
DOI: 10.1007/s00432-024-05909-w
PMCID: PMC11317451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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