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Article

Leveraging Random Effects in Cistrome-Wide Association Studies for Decoding the Genetic Determinants of Prostate Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Sept 2024

Shao Mengting, Tian Min, Chen Kaiyang, Jiang Hangjin, Zhang Shuting, Li Zhenghui, Shen Yan, Chen Feng, Shen Baixin, Cao Chen, Gu Ning

Abstract excerpt

Cistrome-wide association studies (CWAS) are pivotal for identifying genetic determinants of diseases by correlating genetically regulated cistrome states with phenotypes. Traditional CWAS typically develops a model based on cistrome and genotype data to associate predicted cistrome states with phenotypes. The random effect cistrome-wide association study (RECWAS), reevaluates the necessity of cistrome state...

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Identifiers

PMID: 39099406
DOI: 10.1002/advs.202400815
PMCID: PMC11423091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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