Article

chromMAGMA: regulatory element-centric interrogation of risk variants

2022-01-23

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWASs) have identified thousands of genetic variants associated with common polygenic traits. The candidate causal risk variants reside almost exclusively in noncoding regions of the genome and the underlying mechanisms remain elusive for most. Innovative approaches are necessary to understand their biological function. Multimarker analysis of genomic annotation...

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Literature Corpus work: b28cfd69-9ebe-563f-819b-60e612fce426
DOI: 10.1101/2022.01.21.477270

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