Article

Identifying proteomic risk factors for overall, aggressive and early onset prostate cancer using Mendelian randomization and tumor spatial transcriptomics

2023-09-22

Abstract excerpt

<h4>Background</h4> Understanding the role of circulating proteins in prostate cancer risk can reveal key biological pathways and identify novel targets for cancer prevention. <h4>Methods</h4> We investigated the association of 2,002 genetically predicted circulating protein levels with risk of prostate cancer overall, and of aggressive and early onset disease, using cis- pQTL Mendelian randomization (MR) and colo...

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Literature Corpus work: 348067f8-2249-5b08-8af1-3c3769971766
DOI: 10.1101/2023.09.21.23295864

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