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Article

Gene regulatory mechanisms underpinning prostate cancer susceptibility.

Nature genetics - 1 Apr 2016

Whitington Thomas, Gao Ping, Song Wei, Ross-Adams Helen, Lamb Alastair D, Yang Yuehong, Svezia Ilaria, Klevebring Daniel, Mills Ian G, Karlsson Robert, Halim Silvia, Dunning Mark J, Egevad Lars, Warren Anne Y, Neal David E, Grönberg Henrik, Lindberg Johan, Wei Gong-Hong, Wiklund Fredrik

Abstract excerpt

Molecular characterization of genome-wide association study (GWAS) loci can uncover key genes and biological mechanisms underpinning complex traits and diseases. Here we present deep, high-throughput characterization of gene regulatory mechanisms underlying prostate cancer risk loci. Our methodology integrates data from 295 prostate cancer chromatin immunoprecipitation and sequencing experiments with genotype and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26950096
DOI: 10.1038/ng.3523

Genes

FOXA1
HOXB13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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