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A Comprehensive Investigation of Genomic Variants in Prostate Cancer Reveals 30 Putative Regulatory Variants.

International journal of molecular sciences - 27 Jan 2023

Labani Mahdieh, Beheshti Amin, Argha Ahmadreza, Alinejad-Rokny Hamid

Abstract excerpt

Prostate cancer (PC) is the most frequently diagnosed non-skin cancer in the world. Previous studies have shown that genomic alterations represent the most common mechanism for molecular alterations responsible for the development and progression of PC. This highlights the importance of identifying functional genomic variants for early detection in high-risk PC individuals. Great efforts have been made to...

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Chromatin
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Neoplasms

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PMID: 36768794
DOI: 10.3390/ijms24032472
PMCID: PMC9916892

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