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Article

Incorporation of Edited MRS into Clinical Practice May Improve Care of Patients with IDH-Mutant Glioma.

AJNR. American journal of neuroradiology - 8 Jan 2025

Nichelli Lucia, Cadin Capucine, Lazzari Patrizia, Mathon Bertrand, Touat Mehdi, Sanson Marc, Bielle Franck, Marjańska Małgorzata, Lehéricy Stéphane, Branzoli Francesca

Abstract excerpt

BACKGROUND AND PURPOSE: Isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion classify adult-type diffuse gliomas into 3 tumor subtypes with distinct prognoses. We aimed to evaluate the performance of edited MR spectroscopy for glioma subtyping in a clinical setting, via the quantification of D-2-hydroxyglutarate (2HG) and cystathionine. The delay between this noninvasive classification and the integrated...

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Identifiers

PMID: 38997123
DOI: 10.3174/ajnr.A8413
PMCID: PMC11735446

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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