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Article

A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy

2018-12-13

Abstract excerpt

The oncogenes that are expressed in gliomas reprogram particular pathways of glucose, amino acid, and fatty acid metabolism. Mutations in isocitrate dehydrogenase genes (IDH1/2) in diffuse gliomas are associated with abnormally high levels of 2-hydroxyglutarate (2-HG) levels. The aim of this study was to determine whether metabolic reprogramming associated with IDH mutant gliomas leads to additional 1H MRS-detecta...

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Literature Corpus work
e72b5515-b1da-586a-88f9-b53e91c8a778
DOI
10.20944/preprints201812.0168.v1
Open publication

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A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR SpectroscopyDOI 10.20944/preprints201812.0168.v1
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