Article

The temporal evolution of cancer hallmarks

2024-01-23

Abstract excerpt

Cancer hallmarks describe key physiological characteristics that distinguish cancers from normal tissues. The temporal order in which these hallmarks appear during cancer pathogenesis is of interest from both evolutionary and clinical perspectives but has not been investigated before. Here, we order hallmarks based on the allele frequency and selective advantage of mutations in cancer hallmark genes across >10k un...

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Literature Corpus work: 571720cc-a6d9-5575-bb2d-3de3202e8e7b
DOI: 10.1101/2024.01.21.576566

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