Article

Genetic immune escape landscape in primary and metastatic cancer

2022-02-25

Abstract excerpt

Immune surveillance escape is a hallmark of tumorigenesis 1 . Multiple studies have characterized the immune escape landscape across several untreated early-stage primary cancer types 2–4 . However, whether late-stage treated metastatic tumors present differences in genetic immune escape (GIE) prevalence and dynamics remains unclear. Here, we performed a pan-cancer characterization of GIE prevalence across six i...

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Literature Corpus work: 3cb41492-8596-52a3-9a94-fd03ea02b4af
DOI: 10.1101/2022.02.23.481444

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