Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tramadol intoxication in children: An emerging issue.

Therapie - 1 Jan 2000

Drevin Guillaume, Picard Nicolas, Baudriller Antoine, Pena-Martin Maria, Ferec Séverine, Leuger Laurent, Briet Marie, Abbara Chadi

Abstract excerpt

BACKGROUND: Prescribing tramadol in children raises safety concerns. In Europe, tramadol is still approved and licensed for use in children over 1-3 years of age, depending on the country. In this context, the authors report a case of a tramadol overdose in a 5-year-old-child with a medical history of homozygous sickle cell disease. METHODS: Tramadol and M1 were quantified using liquid chromatography with a diode...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Anemia, Sickle Cell
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Genotype

Source

Identifiers

PMID: 38871543
DOI: 10.1016/j.therap.2024.05.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tramadol intoxication in children: An emerging issue.PMID 38871543Read ↗

Assessment of tramadol pharmacokinetics in correlation with CYP2D6 and clinical symptoms.Semantic proximity Read ↗

Trends in Tramadol: Pharmacology, Metabolism, and Misuse.Semantic proximity Read ↗

Massive tramadol ingestion resulting in fatal brain injury - a pharmacokinetic study with discussion on the involved mechanisms of toxicity.Semantic proximity Read ↗

Role of Pharmacogenetics on Tramadol Pharmacokinetics: A Population Pharmacokinetic Model.Semantic proximity Read ↗

Tramadol-related fatalities: Metabolic ratios & SNPs/INDELs belonging to UGT1A8, UGT2B7, ABCC2, and SLC22A1.Semantic proximity Read ↗

A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol.Semantic proximity Read ↗

Effects of the CYP2D6 gene duplication on the pharmacokinetics and pharmacodynamics of tramadol.Semantic proximity Read ↗

Tramadol-Induced Seizures in an Elderly Patient Without Comorbidities: A Case ReportSemantic proximity Read ↗

Sequencing CYP2D6 for the detection of poor-metabolizers in post-mortem blood samples with tramadol.Semantic proximity Read ↗

Metabolic ratios and SNPs implicated in tramadol-related deaths.Semantic proximity Read ↗

Pharmacogenomics for the forensic toxicologist.Semantic proximity Read ↗

Influence of CYP2D6 phenotype on the pharmacokinetics and pharmacodynamics of tramadol in patients treated for post-operative pain management.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.