Article

Tramadol-Induced Seizures in an Elderly Patient Without Comorbidities: A Case Report

2025-10-14

Abstract excerpt

<title>Abstract</title> <p>Background Tramadol is a widely used analgesic for moderate to severe pain due to its dual mechanism of µ-opioid receptor agonism and monoaminergic reuptake inhibition. While generally perceived as safe, it has been increasingly associated with neurotoxic side effects, particularly seizures. These adverse effects are commonly reported in patients with epilepsy, polypharmacy, or organ dy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1e18e606-a634-5f94-a614-d14d1e6fb874
DOI: 10.21203/rs.3.rs-7837568/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Tramadol-Induced Seizures in an Elderly Patient Without Comorbidities: A Case ReportDOI 10.21203/rs.3.rs-7837568/v1Read

Massive tramadol ingestion resulting in fatal brain injury - a pharmacokinetic study with discussion on the involved mechanisms of toxicity.Semantic proximity Read

Common Causes and Characteristics of Adverse Drug Reactions in Older Adults: A Retrospective StudySemantic proximity Read

Trends in Tramadol: Pharmacology, Metabolism, and Misuse.Semantic proximity Read

Tramadol intoxication in children: An emerging issue.Semantic proximity Read

The Impact of Excessive Paracetamol Use on the Human Body: A Comprehensive ReviewSemantic proximity Read

Systematic Evaluation of Adverse Drug Reactions Associated with Benzodiazepine Utilization: A Comprehensive ReviewSemantic proximity Read

A comparative study of remimazolam and midazolam in elderly patients during general anesthesia：a randomized controlled studySemantic proximity Read

Reversal of delirium but induction of coma following flumazenil administration in multidrug intoxication suicide attempt involving quetiapine and medazepam: a case reportSemantic proximity Read

Multi-centric Phase III, single-arm, open-label clinical study to assess clinical safety, tolerability, and efficacy of intravenous lacosamide in focal onset seizuresSemantic proximity Read

Cardiac arrest after small doses ropivacaine: Local Anesthetic Systemic Toxicity in the course of continuous femoral nerve blockadeSemantic proximity Read

Review or Updates on the clinical pharmacokinetics of levetiracetamSemantic proximity Read

The safety and efficacy of anesthesia induction and maintenance with remimazolam besylateon in elderly patients undergoing ureteroscopic laser lithotripsySemantic proximity Read