Article
Causal association of circulating metabolites with diabetic retinopathy: a bidirectional Mendelian randomization analysis.
Frontiers in endocrinology - 1 Jan 2024
Li Bo, Zhao Xu, Xie Wanrun, Hong Zhenzhen, Cao Ye, Ding Yan, Zhang Yi
Abstract excerpt
Introduction: The retina is a highly metabolically active tissue, and there is a lack of clarity about the relationship between metabolites and diabetic retinopathy (DR). This study used two-sample bidirectional Mendelian randomization (MR) analyses to identify causal relationships between metabolites and DR. Methods: Genetic variants were selected from the open-access Genome-Wide Association Studies (GWAS)...
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