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Article

Causality of Blood Metabolites on Proliferative Diabetic Retinopathy: Insights From a Genetic Perspective.

Journal of diabetes research - 1 Jan 2024

Wang Zhaoxiang, Lu Bing, Zhang Li, Xia Yuwen, Shao Xiaoping, Zhong Shao

Abstract excerpt

Background: Our goal was to examine the causal link between blood metabolites, their ratios, and the risk of developing proliferative diabetic retinopathy (PDR) from a genetic insight. Methods: Summary-level data about 1400 blood metabolites and their ratios, as well as PDR, were sourced from prior genome-wide association studies (GWAS). A two-sample univariate and multivariate Mendelian randomization (MR)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39512998
DOI: 10.1155/2024/6828908
PMCID: PMC11540900

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