Article
Causal association between metabolites and age-related macular degeneration: a bidirectional two-sample mendelian randomization study.
Hereditas - 20 Dec 2024
Liu Zhen-Yu, Zhang Hang, Sun Xiu-Li, Liu Jian-Ying
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly population. Accumulating evidence has revealed the possible association between metabolites and AMD. This study aimed to assess the effect of plasma metabolites on AMD and its two subtypes using a bidirectional two-sample Mendelian randomization approach. METHODS: The causality between plasma metabolites...
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