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Article

Genetic Evidence for Causal Effects of Blood Metabolites on Age-Related Macular Degeneration and its Subtypes.

Translational vision science & technology - 2 Mar 2026

Zhang Keting, Jia Lanbo, Zhao Chunbing, Wang Yining, Wei Pinghui, Han Guoge

Abstract excerpt

Purpose: Age-related macular degeneration (AMD) is a predominant cause of permanent vision impairment among older individuals. Despite available treatments for advanced disease, a comprehensive understanding of the pathogenesis, specifically the pivotal causal pathways, remains elusive. This study aims to assess the causal effects of 1400 serum metabolites and their ratios on 3 AMD subtypes using Mendelian...

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Identifiers

PMID: 41885545
DOI: 10.1167/tvst.15.3.31
PMCID: PMC13037742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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