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Article

Causal influence of plasma metabolites on age-related macular degeneration: A Mendelian randomization study.

Medicine - 13 Sept 2024

Wang Tao, Huang Chun, Li Jinshuai, Wu Xiangjian, Fu Xiaoyan, Hu Yimin, Wu Geping, Yang Chunfeng, Chen Sheng

Abstract excerpt

Using genome-wide association study data from European populations, this research clarifies the causal relationship between plasma metabolites and age-related macular degeneration (AMD) and employs Metabo Analyst 5.0 for enrichment analysis to investigate their metabolic pathways. Employing Mendelian randomization analysis, this study leveraged single nucleotide polymorphisms significantly associated with plasma...

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PMID: 39287235
DOI: 10.1097/MD.0000000000039400
PMCID: PMC11404906

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