Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationship between plasma metabolites and hypertension: A Mendelian randomization study.

Medicine - 3 Oct 2025

Yang Fan, Wu Yuan, Zhu Haixiang, Ye Xiaojian, Tang Leiwen

Abstract excerpt

Observational studies have indicated an association between metabolites and hypertension. However, establishing a causal relationship remains challenging. This study aims to investigate this causal relationship using Mendelian randomization methodology. Genome-wide association study summary statistics for plasma metabolites were obtained from 3 studies, encompassing over 2000 varieties. Genome-wide association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study
Share to Hypertension
Share to Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 41054079
DOI: 10.1097/MD.0000000000045077
PMCID: PMC12499832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationship between plasma metabolites and hypertension: A Mendelian randomization study.PMID 41054079Read ↗

The causal relationship between human blood metabolites and risk of peripheral artery disease: a Mendelian randomization studySemantic proximity Read ↗

From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment.Semantic proximity Read ↗

Causal association of genetically predicted 1400 blood metabolites with inflammatory bowel disease risk: A Mendelian randomization study.Semantic proximity Read ↗

The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization: A powerful method to determine causality of biomarkers in diseasesSemantic proximity Read ↗

Mendelian Randomization Study on Serum Metabolites and Diabetic Nephropathy Risk: Identifying Potential Biomarkers for Early Intervention.Semantic proximity Read ↗

Causal association of circulating metabolites with diabetic retinopathy: a bidirectional Mendelian randomization analysis.Semantic proximity Read ↗

Genetic and Causal Relationship Between Coffee Intake and Cardiometabolic Risks: Cross-Phenotype Association And Mendelian Randomization AnalysisSemantic proximity Read ↗

Mendelian Randomization Analysis as a Tool to Gain Insights into Causes of Diseases: A Primer.Semantic proximity Read ↗

Assessing causal associations of blood counts and biochemical indicators with pulmonary arterial hypertension: a Mendelian randomization study and results from national health and nutrition examination survey 2003-2018.Semantic proximity Read ↗

Mendelian randomization analysis of the causal relationship between serum metabolites and thoracic aortic aneurysm.Semantic proximity Read ↗

Mendelian randomization as a tool for causal inference in human nutrition and metabolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.