Article
Causal relationships between blood metabolites and diabetic retinopathy: a two-sample Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Yang Chongchao, Ma Yan, Yao Mudi, Jiang Qin, Xue Jinsong
Abstract excerpt
Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes, severely affecting patients' vision and even leading to blindness. The development of DR is influenced by metabolic disturbance and genetic factors, including gene polymorphisms. The research aimed to uncover the causal relationships between blood metabolites and DR. Methods: The two-sample mendelian randomization (MR) analysis was...
Topics
- Humans
- Mendelian Randomization Analysis
- Diabetic Retinopathy
- Genome-Wide Association Study
- Polymorphism, Single Nucleotide
