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Article

Evaluation of the rapid Idylla IDH1-2 mutation assay in FFPE glioma samples.

Diagnostic pathology - 25 May 2024

Solomon James P, Munoz-Zuluaga Carlos, Slocum Cheyanne, Dillard Alicia, Cong Lin, Wang Jiajing, Lindeman Neal, Kluk Michael, Liechty Benjamin, Pisapia David, Rennert Hanna, Velu Priya D

Abstract excerpt

IDH1 and IDH2 mutational status is a critical biomarker with diagnostic, prognostic, and treatment implications in glioma. Although IDH1 p.R132H-specific immunohistochemistry is available, it is unable to identify other mutations in IDH1/2. Next-generation sequencing can accurately determine IDH1/2 mutational status but suffers from long turnaround time when urgent treatment planning and initiation is medically...

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Identifiers

PMID: 38796421
DOI: 10.1186/s13000-024-01492-3
PMCID: PMC11128120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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