Article
IDH1/2 mutation detection in gliomas.
Brain tumor pathology - 1 Apr 2015
Arita Hideyuki, Narita Yoshitaka, Yoshida Akihiko, Hashimoto Naoya, Yoshimine Toshiki, Ichimura Koichi
Abstract excerpt
Somatic mutations of isocitrate dehydrogenase 1 and 2 (IDH1/2) are strongly associated with pathological subtypes, genetic profiles, and clinical features in gliomas. The IDH1/2 status is currently regarded as one of the most important molecular markers in gliomas and should be assessed accurately and robustly. However, the methods used for IDH1/2 testing are not fully standardized. The purpose of this paper is...
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