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Article

Evaluation of the Idylla IDH1-2 Mutation Assay for the Detection of IDH Variants in Solid Tumors and Hematological Malignancies.

International journal of molecular sciences - 20 Jan 2026

Gilson Pauline, Muller Marc, Gauchotte Guillaume, Fadil Smahane, Husson Marie, Hanriot Idrissia, Witz Andréa, Dardare Julie, Betz Margaux, Merlin Jean-Louis, Harlé Alexandre

Abstract excerpt

Isocitrate dehydrogenase (IDH) variants can lead to the development and/or progression of various solid tumors and hematological malignancies. IDH testing can guide diagnosis, prognosis, and therapeutic choice and typically relies on NGS, IHC, or PCR-based assays. Here, we evaluated the analytical performance of the Idylla IDH1-2 mutation assay for IDH variant detection using 70 fixed samples from patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41596663
DOI: 10.3390/ijms27021017
PMCID: PMC12842437

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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