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Article

Truncating the spliceosomal 'rope protein' Prp45 results in Htz1 dependent phenotypes.

RNA biology - 1 Jan 2024

Abrhámová Kateřina, Groušlová Martina, Valentová Anna, Hao Xinxin, Liu Beidong, Převorovský Martin, Gahura Ondřej, Půta František, Sunnerhagen Per, Folk Petr

Abstract excerpt

Spliceosome assembly contributes an important but incompletely understood aspect of splicing regulation. Prp45 is a yeast splicing factor which runs as an extended fold through the spliceosome, and which may be important for bringing its components together. We performed a whole genome analysis of the genetic interaction network of the truncated allele of PRP45 (prp45(1-169)) using synthetic genetic array...

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Identifiers

PMID: 38711165
DOI: 10.1080/15476286.2024.2348896
PMCID: PMC11085953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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