Article
Changes in intrahost genetic diversity according to lesion severity in longitudinal HPV16 samples.
Journal of medical virology - 1 May 2024
Costanzi Jean-Marc, Stosic Milan S, Løvestad Alexander H, Ambur Ole H, Rounge Trine B, Christiansen Irene K
Abstract excerpt
Human papillomavirus type 16 (HPV16) is the most common cause of cervical cancer, but most infections are transient with lesions not progressing to cancer. There is a lack of specific biomarkers for early cancer risk stratification. This study aimed to explore the intrahost HPV16 genomic variation in longitudinal samples from HPV16-infected women with different cervical lesion severity (normal, low-grade, and...
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