Article

HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples

2020-11-29

Abstract excerpt

Human papillomavirus 16 and 18 are the most predominant types in cervical cancer. Only a small fraction of HPV infections progress to cancer, indicating that genomic factors, such as minor nucleotide variation caused by APOBEC3 and chromosomal integration, contribute to the carcinogenesis. We analysed minor nucleotide variants (MNVs) and integration in HPV16 and HPV18 positive cervical samples with different morph...

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Literature Corpus work: 645ce5ed-53bb-53ee-8d2c-fd6fa2025ed3
DOI: 10.1101/2020.11.25.20238477

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