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Article

Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome.

Journal of virology - 15 Jun 2018

Hirose Yusuke, Onuki Mamiko, Tenjimbayashi Yuri, Mori Seiichiro, Ishii Yoshiyuki, Takeuchi Takamasa, Tasaka Nobutaka, Satoh Toyomi, Morisada Tohru, Iwata Takashi, Miyamoto Shingo, Matsumoto Koji, Sekizawa Akihiko, Kukimoto Iwao

Abstract excerpt

Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer, accompanied by the accumulation of somatic mutations into the host genome. There are concomitant genetic changes in the HPV genome during viral infection; however, their relevance to cervical carcinogenesis is poorly understood. Here, we explored within-host genetic diversity of HPV by performing deep-sequencing analyses of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Human papillomavirus 16

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Source

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Identifiers

PMID: 29593040
DOI: 10.1128/JVI.00017-18
PMCID: PMC5974501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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