Article
HPV16 Phylogenetic Variants in Anogenital and Head and Neck Cancers: State of the Art and Perspectives.
Viruses - 3 Jun 2024
Galati Luisa, Di Bonito Paola, Marinaro Mariarosaria, Chiantore Maria Vincenza, Gheit Tarik
Abstract excerpt
HPV16 is responsible for approximately 60% and 90% of global HPV-induced cervical and oropharyngeal cancers, respectively. HPV16 intratype variants have been identified by HPV genome sequencing and classified into four phylogenetic lineages (A-D). Our understanding of HPV16 variants mostly derives from epidemiological studies on cervical cancer (CC) in which HPV16 B, C, and D lineages (previously named...
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