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Article

Viral whole genome sequencing reveals high variations in APOBEC3 editing between HPV risk categories.

Journal of medical virology - 1 Oct 2024

Ferré Valentine Marie, Coppée Romain, Gbeasor-Komlanvi Fifonsi A, Vacher Sophie, Bridier-Nahmias Antoine, Bucau Margot, Salou Mounerou, Lameiras Sonia, Couvelard Anne, Dagnra Anoumou Claver, Bieche Ivan, Descamps Diane, Ekouevi Didier K, Ghosn Jade, Charpentier Charlotte

Abstract excerpt

High-risk human papillomavirus (HPV) infections are responsible for cervical cancer. However, little is known about the differences between HPV types and risk categories regarding their genetic diversity and particularly APOBEC3-induced mutations - which contribute to the innate immune response to HPV. Using a capture-based next-generation sequencing, 156 HPV whole genome sequences covering 43 HPV types were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 39400339
DOI: 10.1002/jmv.70002

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