Article
HPV16 genetic variation and the development of cervical cancer worldwide.
British journal of cancer - 15 Jan 2013
Cornet I, Gheit T, Iannacone M R, Vignat J, Sylla B S, Del Mistro A, Franceschi S, Tommasino M, Clifford G M
Abstract excerpt
BACKGROUND: Factors that favour a small proportion of HPV16 infections to progress to cancer are still poorly understood, but several studies have implicated a role of HPV16 genetic variation. METHODS: To evaluate the association between HPV16 genetic variants and cervical cancer risk, we designed a multicentre case-control study based on HPV16-positive cervical samples (1121 cervical cancer cases and 400...
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