Article
Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores: evidence from the China Kadoorie Biobank.
Chinese medical journal - 20 Oct 2023
Yang Songchun, Sun Dong, Sun Zhijia, Yu Canqing, Guo Yu, Si Jiahui, Sun Dianjianyi, Pang Yuanjie, Pei Pei, Yang Ling, Millwood Iona Y, Walters Robin G, Chen Yiping, Du Huaidong, Pang Zengchang, Schmidt Dan, Stevens Rebecca, Clarke Robert, Chen Junshi, Chen Zhengming, Lv Jun, Li Liming
Abstract excerpt
BACKGROUND: Several studies have reported that polygenic risk scores (PRSs) can enhance risk prediction of coronary artery disease (CAD) in European populations. However, research on this topic is far from sufficient in non-European countries, including China. We aimed to evaluate the potential of PRS for predicting CAD for primary prevention in the Chinese population. METHODS: Participants with genome-wide...
Topics
Join the communities discussing this publication.