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Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.

Investigative ophthalmology & visual science - 1 Apr 2024

Williams Brandi L, Zouache Moussa A, Seager Nathan A, Pappas Chris M, Liu Jin, Anstadt Robert A, Hubbard William C, Thomas Julie, Hageman Jill L, Mohler Jennifer, Richards Burt T, Hageman Gregory S

Abstract excerpt

Purpose: The purpose of this study was to determine if levels of the HtrA1 protein in serum or vitreous humor are influenced by genetic risk for age-related macular degeneration (AMD) at the 10q26 locus, age, sex, AMD status, and/or AMD disease severity, and, therefore, to determine the contribution of systemic and ocular HtrA1 to the AMD disease process. Methods: A custom-made sandwich ELISA assay (SCTM ELISA)...

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Share to Chromosomes, Human, Pair 10
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38648039
DOI: 10.1167/iovs.65.4.34
PMCID: PMC11044837

Genes

HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.PMID 38648039Read ↗

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