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Article

HTRA1 rs11200638 variant and AMD risk from a comprehensive analysis about 15,316 subjects.

BMC medical genetics - 15 May 2020

Liu Ying, Jin Huipeng, Wei Dong, Li Wenxiu

Abstract excerpt

BACKGROUND: The high-temperature requirement factor A1 (HTRA1) gene located at 10q26 locus has been associated with age-related macular degenerative (AMD), with the significantly related polymorphism being (rs11200638, -625G/A), however, above association is not consistent. We investigated a comprehensive analysis to evaluate the correlations between rs11200638 polymorphism and AMD susceptibility thoroughly...

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Identifiers

PMID: 32414342
DOI: 10.1186/s12881-020-01047-5
PMCID: PMC7229611

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