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Article

The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples.

Ophthalmology - 1 Nov 2008

Tuo Jingsheng, Ross Robert J, Reed George F, Yan Qing, Wang Jie Jin, Bojanowski Christine M, Chew Emily Y, Feng Xiao, Olsen Timothy W, Ferris Frederick L, Mitchell Paul, Chan Chi-Chao

Abstract excerpt

OBJECTIVE: To assess the association and combined effect on the risk of age-related macular degeneration (AMD) by the HtrA1 and complement factor H (CFH) polymorphisms, smoking, and serum cholesterol. DESIGN: Clinic-based and population-based case control study. PARTICIPANTS: A total of 805 AMD cases and 921 controls from The Eye Clinic of National Eye Institute, Age-Related Eye Diseases Study, Blue Mountain Eye...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18718667
DOI: 10.1016/j.ophtha.2008.05.021
PMCID: PMC2610681

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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