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Article

Prospective Role of PAK6 and 14-3-3γ as Biomarkers for Parkinson's Disease.

Journal of Parkinson's disease - 1 Jan 2024

Giusto Elena, Maistrello Lorenza, Iannotta Lucia, Giusti Veronica, Iovino Ludovica, Bandopadhyay Rina, Antonini Angelo, Bubacco Luigi, Barresi Rita, Plotegher Nicoletta, Greggio Elisa, Civiero Laura

Abstract excerpt

Background: Parkinson's disease is a progressive neurodegenerative disorder mainly distinguished by sporadic etiology, although a genetic component is also well established. Variants in the LRRK2 gene are associated with both familiar and sporadic disease. We have previously shown that PAK6 and 14-3-3γ protein interact with and regulate the activity of LRRK2. Objective: The aim of this study is to quantify PAK6...

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Source

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Identifiers

PMID: 38640169
DOI: 10.3233/JPD-230402
PMCID: PMC11091598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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