Article

Prospective role of PAK6 and 14-3-3γ as biomarkers for Parkinson’s disease

2023-09-25

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD) is a progressive neurodegenerative disorder mainly distinguished by sporadic aetiology, although a genetic component is also well established. Variants in the <italic>LRRK2</italic> gene are associated with both familiar and sporadic forms of the disease. We have previously shown that PAK6 and 14-3-3γ interact with and regulate the activity of LRRK2. In this stu...

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Literature Corpus work: c40320af-5b9b-525a-992a-9e68f8310acf
DOI: 10.21203/rs.3.rs-3334243/v1

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