Article

Prospective role of PAK6 and 14-3-3γ as biomarkers for Parkinson’s disease

2023-04-28

Abstract excerpt

2. <h4>Background</h4> Parkinson’s disease is a progressive neurodegenerative disorder mainly distinguished by sporadic aetiology, although a genetic component is also well established. Variants in the LRRK2 gene are associated with both familiar and sporadic disease. We have previously shown that PAK6 and 14-3-3γ protein interact with and regulate the activity of LRRK2. <h4>Objectives</h4> The aim of this stu...

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Literature Corpus work: 4b43ccc0-2527-5e7e-b5ff-0b4cca97f3ad
DOI: 10.1101/2023.04.28.538525

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