Article
Association between dyslipidemia and the risk of incident chronic kidney disease affected by genetic susceptibility: Polygenic risk score analysis.
PloS one - 1 Jan 2024
Weon Boram, Jang Yunjeong, Jo Jinyeon, Jin Wencheng, Ha Seounguk, Ko Ara, Oh Yun Kyu, Lim Chun Soo, Lee Jung Pyo, Won Sungho, Lee Jeonghwan
Abstract excerpt
BACKGROUND: The effect of dyslipidemia on kidney disease outcomes has been inconclusive, and it requires further clarification. Therefore, we aimed to investigate the effects of genetic factors on the association between dyslipidemia and the risk of chronic kidney disease (CKD) using polygenic risk score (PRS). METHODS: We analyzed data from 373,523 participants from the UK Biobank aged 40-69 years with no...
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