Article

Genome-wide polygenic score with<i>APOL1</i>risk genotypes predicts chronic kidney disease across major continental ancestries

2021-10-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Chronic kidney disease (CKD) is a common complex condition associated with significant morbidity and mortality in the US and worldwide. Early detection is critical for effective prevention of kidney disease progression. Polygenic prediction of CKD could enhance screening and prevention of kidney disease progression, but this approach has not been optimized for risk predictio...

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Literature Corpus work: b76b9573-533e-570d-ae8e-3b9f261096be
DOI: 10.1101/2021.10.25.21265398

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