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Article

Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.

CNS neuroscience & therapeutics - 1 Apr 2024

Xiao Menglin, Cui Xiaoteng, Xu Can, Xin Lei, Zhao Jixing, Yang Shixue, Hong Biao, Tan Yanli, Zhang Jie, Li Xiang, Li Jie, Kang Chunsheng, Fang Chuan

Abstract excerpt

AIMS: To investigate the key factors influencing glioma progression and the emergence of treatment resistance by examining the intrinsic connection between mutations in DNA damage and repair-related genes and the development of chemoresistance in gliomas. METHODS: We conducted a comprehensive analysis of deep-targeted gene sequencing data from 228 glioma samples. This involved identifying differentially mutated...

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Identifiers

PMID: 38600891
DOI: 10.1111/cns.14698
PMCID: PMC11007544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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