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Article

Comprehensive somatic mutational analysis in glioblastoma: Implications for precision medicine approaches.

PloS one - 1 Jan 2024

Azimi Parisa, Karimpour Mina, Yazdanian Taravat, Totonchi Mehdi, Ahmadiani Abolhassan

Abstract excerpt

Glioblastoma multiforme (GBM), a malignant neoplasm originating from glial cells, remains challenging to treat despite the current standard treatment approach that involves maximal safe surgical resection, radiotherapy, and adjuvant temozolomide chemotherapy. This underscores the critical need to identify new molecular targets for improved therapeutic interventions. The current study aimed to explore the somatic...

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Source

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Identifiers

PMID: 38166029
DOI: 10.1371/journal.pone.0295698
PMCID: PMC10760858

Genes

AHNAK2
OBSCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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