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Integrated genomic characterization of cancer genes in glioma

13 Oct 2017

Abstract excerpt

Cancers are caused by the acquisition of somatic mutations. Numerous efforts have been made to characterize the key driver genes and pathways in glioma, however, the etiology of glioma is still not completely known. This study was implemented to characterize driver genes in glioma independently of somatic mutation frequencies. Driver genes and pathways were predicted by OncodriveCLUST, OncodriveFM, Icages, Drgap...

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PMID: 29046615
DOI: 10.1186/s12935-017-0458-y

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